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After PPs treatment OS was improved through the upregulation of the Nrf2, HO-1, NOS, MDA and PI3K levels (Chen X

Slower titration also allows assessment of nausea, appetite suppression, and gastrointestinal tolerance

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As a result of the normalization of the ratio of acyl-CoA/CoA-OH in mitochondria, the reverse inhibition of -oxidation occurs, which, in turn, leads to the formation of acetyl-CoA