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Some patients may notice increased awareness of breathing during physical activity as they become more active following weight loss

A biological one

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Biochimica et Biophysica Acta-Mol Basis Dis 1864(9):28142821 Gu Y, Sun L, He Y, Yang L, Deng C, Zhou R et al (2023) Comparative efficacy of glucagon-like peptide 1 (GLP-1) receptor agonists, pioglitazone and vitamin E for liver histology among patients with nonalcoholic fatty liver disease: systematic review and pilot network meta-analysis of randomized controlled trials

These reports prompted regulatory agencies in multiple countries to investigate whether a causal relationship exists between these medications and suicidal thoughts or behaviors