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Likewise, PET-CT scans of mice fed a high-fat diet (HFD) showed that metformin increased glucose uptake on the basolateral side of the intestine, leading to enhanced glucose tolerance in a manner that depended on the dosage (Tobar et al., 2023)

Tirzepatide (brand name Mounjaro/Zepbound) is a dual GIP/GLP-1 receptor agonist that has shown even greater weight loss efficacy than semaglutide alone in head-to-head trials

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It neutralizes free radicals, protecting skin cells from their harmful effects and potentially reducing inflammation, a key player in melasma development

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