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[1] [4] In the type 2 diabetes cohort, retatrutide also produced clinically meaningful weight loss alongside reductions in HbA1c

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Cancer risk from alcohol is not binary (safe / not safe) but proportional more alcohol generally means higher incremental risk

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Adverse events such as diarrhea, constipation, nausea, and vomiting associated with the GLP-1 RAs overlap with those seen with cancer treatments, so the patient who is undergoing treatment with an emetogenic regimen for cancer will likely experience additional weight loss, which can lead to nutritional deficiencies, loss of lean muscle mass, and loss of bone mass