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Building on these classic observations, more mechanistic studies have proposed functional explanations for the relationship between the Bacteroidetes to Firmicutes ratio and host energy balance

The potential mechanisms were found to be related to regulating neurotransmitter (5-Hydroxytryptamine) and inflammatory factor levels, and importantly, blocking the JAK2/STAT3 signaling pathway effectively alleviated depressive symptoms in BC combined with depression mice, inhibiting tumor progression (Kumar and Roy, 2023)

Martnez Damonte, S

Hiebl, J