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6,10 AT functions in cutaneous homeostasis primarily in 3 ways: through paracrine signaling to reticular fibroblasts and keratinocytes, direct extracellular matrix (ECM) secretion, and structural support

This effect is particularly beneficial given the strong link between obesity and type 2 diabetes, as weight loss can lead to improvements in insulin sensitivity and a reduction in cardiovascular risk factors

The gene acts more like a loaded gun than a guaranteed outcome

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Sha had been obese for more than a decade, he said, and decided to take the pills after being introduced to them by his doctor girlfriend

Results from meta-regression analysis showed that the duration of treatment accounted for 41.01% of heterogeneity among studies