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Rasic D, Drmic D, Sever M, Baric M, Grgic T, et al

Clin Epigenetics

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The immune system generates massive amounts of reactive oxygen species (ROS) as chemical weapons against the invading pathogen

Mechanisms of Protection: Upregulation of superoxide dismutase (SOD) and catalase key antioxidant enzymes Suppression of pro-inflammatory cytokine production (IL-6, TNF-) Activation of cellular repair pathways (autophagy, protein synthesis) Restoration of wound-healing fibroblast function Clinical Evidence & Research Applications Skin Regeneration & Photoaging Topical GHK-Cu has been investigated in multiple clinical trials examining its effects on sun-damaged skin (photoaging), wrinkles, skin thickness, and elasticity

This suggests that the expression of different isoforms of the AsA-GSH pathway enzymes is under intricate regulation