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Adjust dosages as necessary in consultation with a healthcare provider
Ingredients with strong evidence and low irritation risk are the best starting point: glutathione, tranexamic acid, azelaic acid, niacinamide, and kojic acid
Nonetheless, it is believed that the tumor-inhibiting effect is partially mediated by several biological changes, such as increased apoptosis rates in cancer cells, decreased circulating blood glucose levels, inhibited insulin-like growth factor 1 (IGF-1) signaling, reduced insulin levels, and mediators that regulate metabolic pathway activation and inhibit angiogenesis
PMID: 24245565
CDC42 is also known to be involved in cancer development and metastasis by the fasciculation of F-actin in the filamentous pseudopodia of the cells [88]