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Outcomes of interest for this review included cellular factors such as neurotrophins (i.e., brain derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1)) and inflammatory markers, hemodynamic and functional measures for any cerebral conduit arteries (e.g., neck artery compliance/stiffness, blood flow, reactivity) and cerebral arteries (e.g., cerebral hemodynamics, blood flow, reactivity, autoregulation), brain structure (regional grey matter integrity, white matter lesions, diffusion tensor images, blood-brain barrier (BBB) integrity), clinical neurodegenerative measures (amyloid deposition, tau neurofibrillary tangles, inflammatory markers), functional connectivity (functional magnetic resonance imaging (fMRI) indices), and cognitive function

Regulatory oversight for exosomes and PRP is strong, positioning these treatments as safer alternatives to unapproved stem cell interventions

A study from the International Journal of Epidemiology established an even more dire connection

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I probably will not use either one going forward because the difference for me was not that great compared to the extra expense

In addition, antioxidant vitamins such as ascorbic acid and tocopherols have been reported to improve insulin sensitivity [188]