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High levels of caffeine can also stress the adrenal glands, indirectly affecting the body's ability to maintain balanced glutathione levels

Reactive oxygen species (ROS), including hydroxyl radicals (OH - ), hydrogen peroxide (H 2 O 2 ), superoxide anions (O 2 ), and lipid peroxides, are molecules highly reactive because of the presence of unpaired electrons (19, 20)

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10.1097/HEP.0000000000000323 Hepatology