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Tirzepatide (Mounjaro, Zepbound) tends to produce greater weight loss than semaglutide (Ozempic, Wegovy), which may mean more aggressive caloric restriction and potentially larger nutritional gaps

10.1186/s13024-025-00857-6 476 WeisS.SchwiertzA.UngerM

PMID: 17147644.

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Some users have even reported reduced cravings for alcohol and other compulsive behaviors, pointing to GLP-1's effects on the brain's reward circuitry