Exendin-4 was ultimately synthesized to Exenatide, a GLP-1RA with a half-life sufficient to permit clinical use in treating type 2 diabetes, the first in a new generation of drugs that followed
The GLP-1 patches advertised online are dietary supplements, not pharmaceuticals, and they contain none of the active GLP-1 drug ingredients like semaglutide or tirzepatide
Activation of this receptor also slows gastric emptying, promotes satiety, and reduces food intake, contributing to weight management and appetite control
They are marketed as nutritional supplements or drops and may make fraudulent use of the logos of regulatory authorities such as Swissmedic and carry invented quality marks with the aim of deliberately deceiving consumers
Anaesth Rep 2024;12:e12278.ArticlePubMedPMC 18
Most gastrointestinal side effects occur during the first month