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diabetes, hypertension, smoking, physical inactivity, and no daily alcohol intake (light alcohol consumption is heart-healthy) presented larger risks for the disease

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Changes in the Ser107 and Gln204 dihedral angles make the H site more hydrophobic in the Sj26GSTHEX complex relative to the ligand-free structure

While Tirzepatides cardiovascular impact is still under investigation, this could be a key factor for those with preexisting heart conditions

Also, this scientific paper is derived from a research grant funded by Taibah University, Madinah, Kingdom of Saudi Arabia - with grant number (447-16-1175) Ethics declarations Ethics approval and consent to participate Ethical approval for all procedures was obtained from the Mansoura University Animal Care and Use Committee (MU- ACUC-M.V.R.25.10.249)