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The historical reliance on laparoscopy as the gold standard for diagnosis has also contributed to delays, as access to surgical evaluation may be limited and often reserved for advanced or refractory cases

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Second, although our data establish that SLC25A39 is crucial for mitochondrial homeostasis, the molecular interactions between SLC25A39 and oncogenic signaling networks, as well as its impact on regulating mitochondrial metabolism, remain undefined and will be the focus of our future work