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For clinicians, that conversation needs to happen before switching GLP-1 treatment
Conservative management strategies include: Optimize gastrointestinal function: Address constipation proactively with adequate hydration (individualized to the patient's cardiovascular and renal status), dietary fiber supplementation, and when necessary, osmotic laxatives such as polyethylene glycol
Its essential for the patient to openly communicate their expectations during this phase, as it helps in setting realistic goals and ensures that the surgical plan aligns with these expectations
If retatrutide receives marketing authorisation in the future, it would likely be subject to additional monitoring indicated by a black triangle () symbol which encourages enhanced Yellow Card reporting for new medicines to help identify any rare or delayed effects not captured in pre-approval trials
Ultra-processed diet Chronic systemic inflammation from a diet of ultra-processed food cancels regenerative signaling
Probiotics for semaglutide users may help reduce gastrointestinal side effects
