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For example, GLP-1RAs have been shown to reduce retinal ganglion cell loss by lowering pro-apoptotic signals such as Bax and enhancing anti-apoptotic signaling via Bcl-2 pathways

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Most protocols run for 4-12 weeks, with some individuals benefiting from ongoing use or periodic cycles

Rybelsus (oral semaglutide), for example, requires taking it on an empty stomach with no more than 4 ounces of water, then waiting at least 30 minutes before eating, drinking, or taking other medications

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