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Phentermine works by stimulating the release of chemicals in the brain that reduce hunger, making it easier for individuals to consume fewer calories

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Obesity continues to rise among the general population, resulting in an epidemic that shows no significant signs of decline

Epigenetic regulation plays a pivotal role in the pathogenesis of DKD, providing a molecular basis for the phenomenon of metabolic memorywhereby transient episodes of hyperglycemia induce long-lasting pathological changes in renal cells (64, 65)

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Perhaps drugs that increase metabolic rate (instead of energy intake) and prevent the adaptive decrease in metabolic rate induced by food intake-reducing drugs (incl