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The study quantified cytokines, neurotransmitters, oxidative stress markers and detoxification enzymes using ELISA-based assays, revealing that VPA exposure disrupted glutathione balance, increased IL-6, CYP450 and glutamate, and reduced serotonin and IFN-, while curcumin partially restored these alterations ( Furthermore, Yang and Bhandari employed a PPA-induced rat model of autism, using male-only Sprague-Dawley rats that received intracerebroventricular infusions of 1M PPA

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Additionally, increased circulation and oxygen delivery to injured or damaged areas helps with cell turnover

Parkinsons Dis 2011, 314082 (2011)

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[20] Wishart DS, Feunang YD, Guo AC, et al