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Chen YB, Li J, Quan Z, Li Y, Li Y, Tang

2b, 3d, and Supplementary Figs

Numerous studies indicate that phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway plays a critical role in cancer progression, making it a promising target for screening natural therapeutic candidates (Ong et al

However, Ca 2+ overload (induced by pro-inflammatory cytokines) inhibits these flippases and activates scramblases, resulting in PS exposure on the cell surface (Lanser et al., 2021)

PJB acknowledges support from award RO1CA164719 from the National Cancer Institute (NCI), National Institutes of Health (NIH), USA