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Practical management considerations include: Dose review: If the heart rate increase is dose-dependent and symptomatic, reducing the dose or slowing the titration schedule where permitted by the trial protocol may help mitigate the effect whilst preserving therapeutic benefit

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Although not yet FDA-approved, Retatrutide is gaining attention as the most potent weight loss peptide ever studied

Marathe CS, Rayner CK, Jones KL, Horowitz M

Pulmonary Aspiration During General Anesthesia or Deep Sedation Inform patients that liraglutide injection may cause their stomach to empty more slowly which may lead to complications with anesthesia or deep sedation during planned surgeries or procedures