Adding cagrilintide to tirzepatide Theoretical protocol (not clinically studied): If on tirzepatide 10-15mg: Stable on tirzepatide for 4+ weeks Continue tirzepatide at current dose Add cagrilintide 0.6mg weekly Standard cagrilintide titration to 2.4mg Rationale: Tirzepatide is dual GIP/GLP-1 (very powerful alone) Adding amylin pathway could theoretically enhance No clinical data on this combination Uncertain if additional benefit over tirzepatide alone Concerns: GI side effects may be severe (both slow gastric emptying) Tirzepatide already produces 15-22% weight loss alone Unclear if cagrilintide adds meaningful benefit Expensive combination Verdict: Wait for clinical data
These associations were independent of demographic, socioeconomic, lifestyle factors, use of medications that could have an effect on serum vitamin B12 levels, dietary supplement use and fasting time
Its already happening, right
For example, Cigna suggests using a dedicated obesity management program as part of the medical benefit, alongside standard pharmacy benefit rules for the drugs
doi: 10.1016/j.intimp.2024.113174 12 HanLFuQDengCLuoLXiangTZhaoH
What happens if you use expired Ozempic