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Dai et al

The documented protocol starts at 2.5 mg once weekly as a tolerability dose, then titrates up roughly every four weeks 5, 7.5, 10, 12.5, up to a 15 mg maximum maintenance dose

Folate deficiency during this period is associated with the development of autism spectrum disorders in children, neural tube irregularity, and brain development defects in the fetus and brain function in later life (30, 68, 69)

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Melatonin is the hormone that helps control the bodys sleep cycle