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MET promoter region in more than 200 families with ASD (Figure 3)

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5-Amino-1MQ is a substrate-mimetic inhibitor that occupies the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)

The peptide contains no cysteine but does have susceptible backbone amide bonds and side-chain groups that can be oxidized under ambient conditions