The significance of this finding remains unclear, but it does remind us that adipose tissue secretes proteins and hormones which may be involved in the pathogenesis of IIH
VSMF: vascular smooth muscle fiber
La expresin de GLP-1R en tejido adiposo subcutneo, visceral y epicrdico es conocida, aunque es controvertida a nivel de los adipocitos2,3
The result is slower transit, harder stool, and a patient who did not expect this to be part of the experience
For type 2 diabetes, the modern bar isnt just does it lower the number, its does it prevent heart attacks, strokes, and kidney decline. The injectable GLP-1s earned their place by proving that in dedicated outcomes trials, and this drug will have to as well. Further research, Carroll said, should also smartly test different starting doses and escalation speeds and how they impact potential side effects, and a rigorous head-to-head comparison against what oral GLP-1 options are already available
- Eva Madrid , co-lead researcher from Universidad de Valparaso, Chile