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doi: 10.2337/dbi19-0027 4 CapozziMEDAlessioDACampbellJE

The altered levels of aldosterone likely explain the hypokalemia and metabolic alkalosis presenting with Gitelman syndrome

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Typical Treatment Duration: Usually prescribed for 12 weeks or less, though doctors sometimes order it for longer-term chronic weight management

Discontinuation rates due to adverse events (12.2% and 18.2% vs 4.0% with placebo) were highly correlated with baseline BMI and included discontinuations for perceived excessive weight loss

Specific receptor sites for pyridoxal 5'-phosphate and pyridoxal 5'-deoxymethylenephosphonate at the and NH2-terminal regions of hemoglobin