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Another important aim in regulating ferroptosis during glutamine metabolism is the targeting of Glutaminase 2 (GLS2), a crucial mitochondrial glutaminase that has recently been studied and recognized as a fresh transcriptional objective of p53 [79]

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Incorporation of Ga(III) in place of iron disrupts the iron-dependent redox process as Ga(III) cannot be reduced to Ga(II) under physiological conditions, and thus cannot be liberated from porphyrins by haem oxygenase ( A

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The 64 integrin promotes resistance to ferroptosis