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The compound shows effectiveness across a wide dose range in animal studies (10 ng/kg to 10 mcg/kg producing comparable results), suggesting that more is not necessarily better

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This work represents one of the first demonstrations of FOXO4-DRI activity in primary human cells, supporting translational relevance beyond the initial mouse model findings

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Preclinical studies combining BPC-157 with growth hormone demonstrated enhanced healing compared to either agent alone, consistent with BPC-157's mechanism of upregulating growth hormone receptor expression