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REIMAGINE 3 was a 40-week efficacy and safety phase 3 trial of CagriSema 2.4 mg/2.4 mg and 1 mg/1 mg once-weekly versus placebo in 274 adults with type 2 diabetes as add-on to once-daily basal insulin with or without metformin

The result suggests that people with autism regulate these chemicals differently than typical individuals do

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[7] So the honest one-line summary is that both build on GLP-1 but recruit a different second pathway amylin for CagriSema, GIP for tirzepatide and there is a further structural difference underneath that: CagriSema achieves its dual action with two separate peptides, while tirzepatide achieves its dual action with one