GLP-1R agonists effect(s) on vascular smooth muscle cells are equally important to those on endothelial cells with several favorable responses being reported, including enhanced differentiation, attenuated response to reactive oxygen species, reduced vascular remodeling through improved mitochondrial activity and dynamics, and the prevention of aberrant migration [65]
It is not the end of the analysis
Side effects often appear during the early weeks of treatment or after dose increases
While IGF-1 (either form) commands the body to produce new satellite cells to heal a torn bicep or sore knee, BPC-157 commands the body to rebuild the delicate network of blood vessels strictly required to feed those new cells oxygen and nutrients
PlexusDx recommends a focused, personalized approach: start with compounded tirzepatide (or an alternative GLP-1 agent suited to your genetic profile), optimize through your prescribing provider, and avoid additives unless directed by your medical team
doi: [Springer]