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139,140,141 Recent advancements have aided in restoring autonomic nerve function

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The effect of thiamine occurred independent of control of hyperglycaemia, blood pressure and statin/fibrate therapy, suggesting that high dose thiamine therapy may produce improvements in the prevention of dyslipidaemia and diabetic nephropathy in addition to those produced by current therapy for control of hyperglycaemia, blood pressure, cholesterol and lipids