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Base-case and sensitivity analyses In Table 3, using three times Taiwans GDP as the WTP threshold (US$77,679), the base-case analysis indicated that using a GLP-1RA versus insulin was cost-effective for preventing one case with all-cause mortality or hospitalized hypoglycemia from the payer perspective, and cost-saving from the healthcare sector perspective

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For years, researchers avoided glucagon activation because glucagon raises blood sugar, which seemed counterproductive for a metabolic medication