A manufacturers boxed warning indicates that a personal or family history of medullary carcinoma of the thyroid poses a contraindication for taking semaglutide, liraglutide, or tirzepatide
While these drugs are established for weight loss, their potential utility in reducing binge eating and related symptoms is a promising field of research
Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes (TRANSCEND-T2D-1)
Other Ingredients: Filtered Water, Vegetable Glycerin, Phosphoric Acid, Citric Acid, Malic Acid, Natural (and Artificial) Flavors, Sucralose, Acesulfame-K, Potassium Sorbate (Preservative), Sodium Benzoate (Preservative)
Circulation 2018;137: 4224
06The proposed reward mechanism remains preclinical Rodent studies implicate central GLP-1 signaling in reward-related regions, including the ventral tegmental area and nucleus accumbens