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249 Further, a study conducted in 2010 revealed that treatment of mouse cardiomyocytes with GLP-1 (936 amide) resulted in extracellular signal-regulated kinase phosphorylation, Akt activation and decreased apoptosis caused by hydrogen peroxide stress or hypoxia

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29 As NAGS is needed to activate CPS1, the result is a decrease in carbamoyl phosphate which is the first step in the urea cycle

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