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In this part of the study, the authors demonstrated the GLP-1R was expressed in mural granulosa cells (MGCs), and its expression was decreased in the PCOS model

32 A recent systematic review and meta-analysis supporting these findings also showed that GLP-1 RA use was not associated with cholecystitis or gallstones in overweight/obese individuals without diabetes

It is approved only for type 2 diabetes mellitus and chronic weight management in adults with obesity or overweight with weight-related comorbidities

Your Found provider may adjust your other medications before prescribing semaglutide

Gopal Grandhige, MD, FACS, Board-Certified Surgeon Last Reviewed: January 15, 2026 GLP-1 medications like Wegovy and Ozempic can cause gastroparesis, a condition where the stomach takes abnormally long to empty its contents

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