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It is available only for in vitro and preclinical laboratory research under appropriate institutional oversight

Sleeve gastrectomy: This procedure reduces the size of the stomach by about 85% by making the stomach a thin sleeve that holds much less food

Drug and vehicle were delivered daily at 3pm, four hours before the onset of the dark cycle, for all experiments

Hormones and therapeutics that act in part via the hypothalamus have made tremendous waves in the past year, underscoring the importance of endocrine regulation in the pathophysiology and treatment of prevalent metabolic disorders such as obesity, diabetes, and fatty liver disease, Abel concludes