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While a causal relationship has not been established, patients with depression or other psychiatric conditions should be monitored for changes in mood or behavior, particularly during the initial weeks of treatment or following dose adjustments

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[DOI] [PubMed] [Google Scholar] 153.Turnbull AV, Ellershaw L, Masters DJ, et al

In humans MEL is produced and secreted by pineal gland as well as small intestine, liver, retinas, lymphocytes and melanocytes in the skin, however only retinal MEL exhibits a circadian rhythm like that in the pineal gland

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Tight and intricate regulatory processes maintain physiological H 2 S levels, while imbalances either in its production or breakdown have deleterious consequences, with high H 2 S levels eventually becoming toxic and/or pathogenic