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The FDA has also approved Ozempic for the prevention of major adverse cardiovascular events (MACE), including heart attack and stroke, in adults with both cardiovascular disease and Type 2 diabetes

Neutralization of reactive oxygen species, up-regulation of enzymatic antioxidants expression and stimulation of the production of non-enzymatic ones (Barzegar & Moosavi-Movahedi, 2011

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Emerging science and drug product development are poised to transform the US GLP-1 landscape, potentially increasing the adoption of these medications even further

Funding This work was in part supported by Fondi di Ateneo from the Universit della Calabria (to CI, MS, MG, and LP) and in part by PON (Programma Operativo Nazionale) Project No