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Fatigue, reported in 8% to 12% of participants, is worth noting because its source matters

Furtado R, Raz I, Goodrich EL, et al

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The weight reductions were accompanied by cardiometabolic profile improvements: decrease in waist circumference, lower systolic and diastolic blood pressure, improved glycemic control including fasting glucose and HbA1c and lower lipid levels

Semaglutide and tirzepatide are used as active pharmaceutical ingredients in FDA-approved brand-name products - Wegovy, Ozempic, Mounjaro, and Zepbound

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