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Interestingly, external iron supplementation has been shown to inhibit M1 polarization by downregulating proinflammatory mediators and iNOS expression through STAT1 inhibition, without impairing phagocytic capacityM1 (108)

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might need to use a lot of PBS Delivering this in a nasal spray would require solid pH control and some carrier to make it sticky or it would just run out

Patch Testing: For topical research, conducting a patch test on a small, inconspicuous area of skin (e.g., the inner forearm) is always a recommended step to assess individual skin compatibility before broader application