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Taken together, the TME interferes with the oxidative metabolism of T cells through multiple pathways, preventing them from performing their effector functions and leading to dysfunction

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This effect may be necessary to prevent hypoglycemia during fasting, but it may also prevent increased aerobic energy turnover during exercise

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We established a stable NRF2 knockdown HaCaT cell line using lentivirus-mediated techniques to delve deeper into NRF2s role in skin inflammation