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On the H+/2e stoichiometry of the respiratory chain *

Indeed, such abnormal presence of mitochondria in circulating red blood cells causes increased oxygen consumption, ROS generation, and hemolysis in SCD patients 50,51

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Cells with ROS were analyzed and quantified by flow cytometry (FACS Calibri)

The phagophore, and hence autophagosome formation requires the generation of an initiation complex named Unc51-like kinase 1 (ULK1) complex composed of ULK1, Atg13, FIP200, and Atg101 (Yang et al., 2015

Which is why there is no officially recommended safe dosage of glutathione as yet