glp 1 mechanism of action diabetes GLP-1 and the kidney: from physiology to pharmacology and outcomes in Emerging Role of GLP-1 Receptor

On this episode of the Huberman Lab podcast, Dr

Turns on DNA repair GHK-Cu activates 47 genes involved in recognizing and repairing DNA damage, the damage that accumulates with age and drives everything from visible aging to disease risk

MK-677 works by: Binding to ghrelin receptors in the hypothalamus and pituitary Stimulating pulsatile GH release Increasing circulating IGF-1 Improving sleep quality and duration (enhanced slow-wave sleep) Benefits Of MK-677 for Recovery 1

Natural GLP-1 cannot be used therapeutically because it is rapidly degraded by the enzyme DPP-4 within 1-2 minutes, requiring continuous intravenous infusion for sustained effect

Reporter Dr Norman Swan visits start-ups which are at the cutting edge of anti-aging research where there are billions of dollars at stake

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