It is worth noting that research comparing GLP-1RAs with six anti-diabetes drugs revealed that there is no significant difference in lowering the risk of HCC between GLP-1RAs and metformin or DDP-4i (Wang et al., 2024)
Whilst the medication is not directly designed to influence reproductive hormones, many women taking tirzepatide have reported changes to their menstrual cycles, prompting questions about whether the drug can affect periods
Whats more, a recent retrospective, multicenter cohort study denied higher occurrence of nonarteritic anterior ischemic optic neuropathy (NAION) in GLP-1RAs users and suggested that its potential benefits for blood glucose control and cardiovascular health likely outweigh its risks (Table 1
That range helps set expectations for how much room there may be for future price reductions if generics eventually enter the market
General Characteristics of the Participants A structured questionnaire was administered to ascertain general aspects [e.g., age, occupation, marital status, residence, substance use, reasons of substance use (e.g., for pleasure, social use, nervousness, or sadness), physical activity], academic aspects, and stressors in school
Zha, S., Li, Z., Cao, Q., Wang, F