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16,17 Topical calcineurin inhibitors have been shown to be effective

[14] [1] In the UK, it is available only as a prolonged-release 150 mg formulation (Zyban) for smoking cessation

Gallbladder disease: rapid weight change and the incretin effect are associated with gallbladder events in the class

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Due to impairment of the MC4R pathway, patients experience accelerated and sustained weight gain, often accompanied by hyperphagia and/or decreased energy expenditure