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In humans, the administration of high doses of VC intravenously for 48 h (50 mg/kg every 6 h) has been shown to reduce the plasma syndecan-1 concentration (129)

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Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells

This is the foundational laboratory study that established copper peptides as a viable hair growth ingredient

doi: 10.1111/j.1464-5491.2005.01567.x, 38 FetissovS

This concept of "biased agonism" is central to understanding why structurally similar compounds acting on the same receptor can produce different downstream effects