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Because theyre worried about potentially having to stop the medication or theyre embarrassed to bring up diarrhea, constipation, and other GI troubles

Observational analyses and randomized clinical trials consistently report nausea, vomiting, diarrhea, constipation, and abdominal discomfort as the most common symptoms, although the distribution of events varies

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Oral metabolic franchise, a broader portfolio of oral small molecule candidates targeting metabolic disease beyond the lead GLP-1 program Recent Highlights: In May 2026, Structure reported positive end-of-Phase 2 feedback from the FDA for aleniglipron, clearing the way to begin a Phase 3 registrational program for chronic weight management in Q3 2026

Hold the needle in place for about 10 seconds to ensure the full dose is delivered

If this is happening to you, try to avoid sulfur-rich foods like broccoli, cabbage, eggs, and garlic