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Zyban is usually prescribed for 7-9 weeks [17] [2] When to Seek Urgent Advice: Contact your GP or seek immediate medical attention if you experience: Severe abdominal pain (potential pancreatitis) Thoughts of self-harm or suicide Seizures or convulsions Severe allergic reactions (rash, difficulty breathing, swelling) Persistent vomiting preventing medication or fluid intake Vision changes or severe headaches Rapid or irregular heartbeat Your prescriber can provide personalised advice based on your individual circumstances, ensuring that the combination of Wegovy and bupropion is appropriate, safe, and optimally managed for your specific health needs