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During 72 weeks of treatment, people taking tirzepatide at doses of 5, 10, or 15 mg lost an average of 15.0%, 19.5%, and 20.9%, respectively, compared with just 3.1% in people taking a placebo
Pancreatic polypeptide inhibits somatostatin secretion
For example, a study in The New England Journal of Medicine (2022) found that non-diabetic adults using semaglutide lost an average of 14.9% of their body weight in 68 weeks more than with diet and exercise alone
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How It Works in Your Body The injection spot can change how well the medication does its job