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Genetic studies on CD have also linked mutations in NLRP3-associated single nucleotide polymorphisms to increased susceptibility to CD (116)

For example, a randomized, double-blind, placebo-controlled trial in patients with overweight or obesity -associated KOA assessed the effects of liraglutide (3 mg/day) over 52 weeks as an add-on to dietary guidance [47, 48]

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