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The only trial FDA staff were able to find about the effectiveness of using BPC-157 to treat ulcerative colitis was a meeting abstract reporting on the results of a study using 46 people in which the peptide was given as an enema, not as an injection

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Early reviews suggest potential benefits and call for more controlled studies to understand long-term results

John Hertig, chair of the Collaborative for Evidence-Based Medicines, said allowing compounders to make these peptides sends the message that the FDA is approving them

4.6 Metabolism Plasma, bile, urine, and fecal samples of intact SD rats or BDC rats after a single administration of [3H]BPC157 were analyzed by HPLC combined with a low-energy radionuclide detection technique to obtain the radiometabolite profiles of [3H]BPC157